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. 2024 Jan 24;31(4):562–573. doi: 10.1038/s41417-024-00731-5

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A RanGAP1 mRNA expression levels were higher in multiple cancers than in normal tissues based on TCGA data. B, C The mRNA expression levels of RanGAP1 based on TCGA and GSE68468 data. D, E RanGAP1 mRNA expression levels of patients with primary and metastatic colon cancer based on GEO datasets. F–H The protein expression levels of RanGAP1 were compared between CRC tissues and matched para-cancer tissues (n = 10), and were subsequently analyzed in Tissue Microarray samples of CRC and normal tissue. I The survival analysis between RanGAP1 expression and Recurrence free survival (RFS) of CRC based on KMplot data.