Figure 1.

mRNA expression data of P-gp and MRP-1 in MTLE patients compared to the non-epileptic controls

Both the efflux transporters show up regulation in the patients. a) & c) Fold change in P-gp and MRP-1, respectively in individual MTLE patients; b) & d) Relative expression (ΔΔCt) between MTLE patients and non-epileptic controls; e) P-gp and MRP-1 proteins are overexpressed in MTLE patients compared to the non-epileptic controls with β-actin as standard; f) Relative density of the WB data by densitometric analysis using ImageJ software.

^*P<0.05, ^***P<0.001, ^****P<0.0001 represents significant difference among the study groups (unpaired student t-tests), error bars show the Mean±SE.