Table 3.
Semi-quantitative analysis of IHC of P-gp and MRP-1 using H-score in MTLE patients and non-epileptic controls
Drug-efflux Transporters | TC/SC in 10 HPFs at 40× | H-score | P | ||
---|---|---|---|---|---|
| |||||
Control | Diseased | Control | Diseased | ||
P-gp | 10722/293 | 15181/1175 | 57 | 268 | <0.0001 |
MRP-1 | 16104/374 | 14487/701 | 49 | 183 | 0.0004 |
Abbreviations: TC: Total cells; SC: Stained cells; HPFs: High power fields.