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. 2023 Sep 1;14(5):615–630. doi: 10.32598/bcn.2021.2554.3

Table 4.

Spearman’s rank correlation coefficient, ρ, and P calculated to find out the correlation of P-gp and MRP-1 with duration of epilepsy, duration of drug-resistance and seizure frequency of MTLE patients

Drug-efflux Transporter Duration of Epilepsy Duration of Drug-resistance Frequency of Seizures
MDR-1 ρ 0.03 −0.30 −0.27
p 0.90 0.27 0.31
MRP-1 ρ 0.02 −0.03 −0.39
p 0.92 0.90 0.14

MDR-1: Multidrug-resistance 1; MRP-1: Multidrug-resistance-associated protein-1.