Table 4.
Spearman’s rank correlation coefficient, ρ, and P calculated to find out the correlation of P-gp and MRP-1 with duration of epilepsy, duration of drug-resistance and seizure frequency of MTLE patients
Drug-efflux Transporter | Duration of Epilepsy | Duration of Drug-resistance | Frequency of Seizures | |
---|---|---|---|---|
MDR-1 | ρ | 0.03 | −0.30 | −0.27 |
p | 0.90 | 0.27 | 0.31 | |
MRP-1 | ρ | 0.02 | −0.03 | −0.39 |
p | 0.92 | 0.90 | 0.14 |
MDR-1: Multidrug-resistance 1; MRP-1: Multidrug-resistance-associated protein-1.