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Activity against Hepatitis B Virus ayw1 in HepG2 2.2.15 cells (data from NIAID).
| Compound | EC50 (μM) | EC90 (μM) | CC50 (μM) | SI50 | SI90 |
|---|---|---|---|---|---|
| 11826096 | 1.86 | 15.67 | >100.00 | >54 | >6 |
| 11826091 | 6.53 | 58.15 | >100.00 | >15 | >2 |
| 11826097 | 22.04 | 78.12 | >100.00 | >5 | >1 |
| 11826092 | 2.13 | 26.5 | >100.00 | >47 | >4 |
| 3TC | 0.01771 | 0.541 | >2.00 | >113 | >4 |
