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. 2023 Dec 17;30(4):e14524. doi: 10.1111/cns.14524

FIGURE 3.

FIGURE 3

VPA treatment and HDAC2‐KD improved cauda equina injury by suppressing oxidative stress and NF‐κB‐mediated inflammation. (A–C) ROS level, MDA content, and GSH content of different groups were assessed in different groups were assessed by Elisa assay (N = 5). (D and E) DHE staining and semi‐quantifications in different groups (N = 5). ns = no significant, **p < 0.01; ***p < 0.001. (F–H) The mRNA level of IL‐1β, IL‐6, and TNF‐α in different groups was assessed by qRT‐PCR. (N = 5). *p < 0.05; **p < 0.01; ***p < 0.001. (I and J) Western blotting and semi‐quantifications for p‐P65, P65, p‐IκB, and IκB protein in different groups (N = 5). **p < 0.01; ***p < 0.001.