. 2023 Dec 23;12(3):364–373. doi: 10.1002/ueg2.12513

TABLE 3.

Independent determinants of CAP ≥ 275 dB/m in 1230 individuals from the liver‐bible‐2022 cohort.

	OR ^a	95% c.i. ^a	p‐value ^a	OR ^b	95% c.i. ^b	p‐value ^b	OR ^c	95% c.i. ^c	p‐value ^c
Age, years	1.01	0.99–1.03	0.34	1.02	0.99–1.04	0.094	1.02	1.00–1.04	0.094
BMI, kg/m²	1.27	1.21–1.32	2 × 10 ⁻ ²⁶	1.11	1.04–1.19	0.0019	1.11	1.04–1.19	0.0019
AC, cm	1.09	1.08–1.11	4 × 10 ⁻ ³⁰	1.06	1.03–1.09	8 × 10 ⁻ ⁶	1.06	1.03–1.09	8 × 10 ⁻ ⁶
Insulin, mU/mL	1.06	1.05–1.08	6 × 10 ⁻ ¹⁴	1.03	1.01–1.05	0.0002	1.03	1.01–1.05	0.0002
T2D, yes	8.60	1.97–37.58	0.0042	6.89	1.49–31.78	0.013	6.87	1.49–31.79	0.014
HDL‐C, mg/dL	0.98	0.97–0.99	0.0003	0.98	0.97–0.99	0.0026	0.98	0.97–0.99	0.0026
TSH, mU/L	0.92	0.81–1.03	0.13	0.87	0.76–0.99	0.046	0.87	0.76–0.99	0.046
Alcohol drinks, n/week	1.02	1.00–1.04	0.071	1.02	1.00–1.04	0.056	1.02	1.00–1.04	0.056

Note: Statistically significant values are highlighted in bold.

Abbreviations: 95% c.i., 95% confidence interval; AC, abdominal circumference; BMI, body mass index; CAP, controlled attenuation parameter; HbA1c, glycated hemoglobin; HDL‐C, high‐density lipoprotein cholesterol; HOMA‐IR, homeostatic model assessment for insulin resistance; LDL‐C, low‐density lipoprotein cholesterol; MDS, Mediterranean diet score; OR, odds ratio; T2D, type 2 diabetes; TG, triglycerides; TSH, thyroid‐stimulating hormone.

^{^a}

At logistic regression (unadjusted). Variables were selected at Backward Stepwise Regression analysis: p‐value to leave = 0.10. Variables fitted in backward stepwise regression analysis were age, sex, ethnicity, BMI, obesity, abdominal circumference, glucose, insulin, HOMA‐IR, T2D, hypertension, LDL‐C, HDL‐C, TG, hypercholesterolemia, ferritin, TSH, MDS, MDS >7, number of alcohol drinks/week, number of soft drinks/week, hours of physical activity/week.

^{^b}

At logistic regression, adjusted for sex, ethnicity and reported variables.

^{^c}

At logistic regression, further adjustment for Levothyroxine replacement.