Table 4.
Univariate Comparison of Potential Preoperative Predictors of Gas-Bloat Syndrome 1 Year After Magnetic Sphincter Augmentation
| Characteristic | GBS, N = 65 (13.3%) | No GBS, N = 424 (86.7%) | Odds ratio (95% CI) | p Value |
|---|---|---|---|---|
| Age, y, median (IQR) | 55.4 (42–61) | 58.1 (48–65) | 0.98 (0.96–1.00) | 0.043 |
| Female sex, % | 72.3 | 62.7 | 1.53 (0.68–2.71) | 0.165 |
| BMI, kg/m2, median (IQR) | 28.2 (26–33) | 29 (26–32) | 0.98 (0.92–1.04) | 0.675 |
| Obesity (BMI ≥ 30 kg/m2), % | 43.1 | 41.5 | 1.07 (0.63–1.81) | 0.893 |
| GERD health-related quality of life score, median (IQR) | 46 (31–58) | 30 (17–49) | 1.04 (1.02–1.05) | <0.0001 |
| Total score (>30), % | 77.4 | 47.3 | 3.73 (2.01–6.92) | <0.0001 |
| Heartburn (≥4), % | 45.2 | 28.2 | 2.10 (1.22–3.61) | 0.008 |
| Regurgitation (≥4), % | 43.5 | 26.8 | 2.11 (1.22–3.63) | 0.008 |
| Dysphagia (≥4), % | 30.6 | 12.6 | 3.09 (1.68–5.71) | 0.0003 |
| Bloating (≥4), % | 54.2 | 24.2 | 3.63 (2.08–6.34) | <0.0001 |
| Simethicone use | 12.3 | 6.4 | 2.14 (0.93–4.89) | 0.115 |
| DeMeester score, median (IQR) | 29.6 (15–45) | 30.5 (18–44) | 0.61 (0.33–1.12) | 0.522 |
| LA grade C/D esophagitis, % | 12.3 | 10.1 | 1.30 (0.89–2.86) | 0.662 |
| Presence of hiatal hernia, % | 87.7 | 92.5 | 0.56 (0.25–1.26) | 0.221 |
| Large or paraesophageal hernia, % | 13.8 | 23.1 | 0.56 (0.27–1.15) | 0.108 |
| Delayed gastric emptying, % | 8.0 | 14.7 | 0.60 (0.14–2.57) | 0.519 |
| Device size (≤14 beads), % | 73.8 | 54.2 | 2.35 (1.31–4.20) | 0.003 |
GBS, gas-bloat syndrome; IQR, interquartile range; LA, Los Angeles.