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. 2023 Dec 20;238(5):912–923. doi: 10.1097/XCS.0000000000000928

Table 6.

Comparison of Outcomes Based On the Status of Persistent or Resolved Gas-Bloat Syndrome from 6 Months to 1 Year

Variable 6-mo GBS persistent at 1 y, N = 17 (30.9%) 6-mo GBS resolved by 1 y, N = 38 (69.1%) p Value
GERD-HRQL at 6 mo
 Total score, median (IQR) 29 (14–31) 11 (8–21) 0.033
 Heartburn item, median (IQR) 0 (1–2) 0 (0–2) 0.653
 Regurgitation item, median (IQR) 2 (0–3) 0 (0–2) 0.226
 Dysphagia item, median (IQR) 3 (2–5) 2 (0–3) 0.008
 Gas-bloat item, median (IQR) 5 (4–5) 4 (4–5) 0.211
 Freedom from proton pump inhibitor use, % 80 91.7 0.343
 Patient satisfaction, % 53.3 84.2 0.032
GERD-HRQL at 1 y
 Total score, median (IQR) 26 (15–36) 7 (4–17) 0.0007
 Heartburn item, median (IQR) 1 (0–2) 0 (0–2) 0.168
 Regurgitation item, median (IQR) 2 (0–4) 0 (0–1) 0.026
 Dysphagia item, median (IQR) 3 (2–4) 1 (0–2) 0.002
 Gas-bloat item, median (IQR) 4 (4–5) 2 (1–3) <0.0001
 Freedom from PPI use, % 69.2 96.9 0.020
 Patient satisfaction, % 56.3 80 0.047
Simethicone use, % 52.9 39.5 0.367
pH normalization, % 75 80 0.681

GBS, gas-bloat syndrome; GERD-HRQL, GERD health-related quality of life; IQR, interquartile range.