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. 2023 Dec 20;238(5):912–923. doi: 10.1097/XCS.0000000000000928

Table 7.

Comparison of Outcomes Based On Status of Delayed Gas-Bloat Syndrome

Variable Delayed GBS, N = 25 (8.5%) No GBS, N = 268 (91.5%) p Value
GERD-HRQL at 6 mo
 Total score, median (IQR) 4 (2–9) 4 (1–8) 0.476
 Heartburn item, median (IQR) 0 (0–1) 0 (0–0) 0.156
 Regurgitation item, median (IQR) 0 (0–0) 0 (0–1) 0.617
 Dysphagia item, median (IQR) 0 (0–1) 0 (0–2) 0.407
 Gas-bloat item, median (IQR) 2 (1–3) 1 (0–2) 0.031
 Freedom from PPI use 84 94.6 0.062
 Patient satisfaction 91.7 93.6 0.664
GERD-HRQL at 1 y
 Total score, median (IQR) 10 (5–25) 4 (1–9) <0.0001
 Heartburn item, median (IQR) 1 (0–2) 0 (0–1) 0.073
 Regurgitation item, median (IQR) 1 (0–1) 0 (0–1) 0.112
 Dysphagia item, median (IQR) 1 (0–1) 0 (0–2) 0.569
 Gas-bloat item, median (IQR) 4 (4–4) 1 (0–2) <0.0001
 Freedom from PPI use, % 86.4 94.4 0.149
 Patient satisfaction, % 79.2 92.8 0.037
Simethicone use, % 40 23.9 0.073
pH normalization, % 66.7 72.5 0.544

GBS, gas-bloat syndrome; GERD-HRQL, GERD health-related quality of life; IQR, interquartile range; PPI, proton pump inhibitor.