Skip to main content
. Author manuscript; available in PMC: 2024 Apr 15.
Published in final edited form as: Psychopharmacology (Berl). 2020 May 22;237(8):2367–2380. doi: 10.1007/s00213-020-05540-w

Fig. 5.

Fig. 5

ACTH and cortisol responses to the LPS challenge session. Data are mean ± SEM. a Effect of the LPS challenge on ACTH, compared with saline (n = 13). There were no significant covariates in the model. b Effect of pioglitazone on ACTH response to the LPS challenge (pioglitazone: n = 5; placebo: n = 8). Covariates in the model included family history of alcohol problems and baseline PACS craving score. c Effect of the LPS challenge on cortisol, compared with saline (n = 13). There were no significant covariates in the model. d Effect of pioglitazone on cortisol response to the LPS challenge (pioglitazone: n = 5; placebo: n = 8). Covariates in the model included baseline depression rating from the CPRS and baseline PACS craving score. For detailed statistics, see “Results”