Table 2.
Adverse events: number of enrolled subjects experiencing each event
| Event | Pioglitazone (n = 8) | Placebo (n = 8) |
|---|---|---|
| Abdominal pain | 0 | 1 |
| Abnormal glucose | 1 | 0 |
| Abnormal platelet count | 1 | 0 |
| Acne | 0 | 1 |
| Anxiety | 0 | 1 |
| Asthma exacerbation by viral infection | 1a | 0 |
| Bloating | 1 | 0 |
| Blood in stool | 0 | 1 |
| Blurred vision | 0 | 1 |
| Buzzed | 1 | 0 |
| Chills | 0 | 1 |
| Cold-like symptoms | 0 | 3 |
| Dark urine | 0 | 1 |
| Deep vein thrombosis | 1a | 0 |
| Elevated aspartate aminotransferase | 1 | 0 |
| Elevated creatine kinase | 5b | 1 |
| Fatigue | 0 | 1 |
| Fever | 1 | 0 |
| Frequent urination | 0 | 1 |
| Headache | 2 | 4 |
| Irritability | 0 | 1 |
| Itching | 1 | 1 |
| Lightheaded | 1 | 1 |
| Loss of appetite | 2 | 0 |
| Low red blood count/hemoglobin A1C | 1 | 0 |
| Muscle aches | 1 | 3 |
| Muscle tightness | 0 | 1 |
| Nausea | 1 | 2 |
| Neck pain | 1 | 0 |
| Pain | 2 | 0 |
| Pain in extremity | 1 | 0 |
| Phlebitis | 0 | 1 |
| Sinus pain | 0 | 2 |
| Sleepiness | 1 | 1 |
| Sore throat | 2 | 2 |
| Stomach pain | 1 | 1 |
| Tiredness | 5 | 5 |
| Toothache | 1 | 3 |
| Trouble sleeping | 1 | 0 |
a
Reported as a serious adverse event
b
One occurrence reported as a serious adverse event