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. Author manuscript; available in PMC: 2024 Apr 15.
Published in final edited form as: Mol Psychiatry. 2021 Jun 30;27(1):113–126. doi: 10.1038/s41380-021-01201-2

Fig. 2. Examples of integrative Omics studies on Schizophrenia.

Fig. 2

Eight recent reports were included as representative (two examples in each of those four categories) to demonstrate the usefulness of integrative Omics studies on schizophrenia (SCZ) research for pathogenesis (1), disease classification (2), risk prediction (3), and precise intervention (4). For each study, we briefly summarized the Omics data and the integrative methods used, and then highlighted the key SCZ findings identified by their application. eQTL expression quantitative trait locus, CMC CommonMind Consortium, DLPFC dorsolateral prefrontal cortex, GWAS genome-wide association study, MHC the major histocompatibility complex, cQTL chromatin quantitative trait locus, fMRI functional magnetic resonance imaging, PET positron emission tomography, SPECT single photon emission computed tomography, FSA functional striatal abnormalities, PRS polygenic risk score, ELC early-life complications, co-eQTL co-expression quantitative trait loci, Cmap The Connectivity Map.