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. 2024 Apr 15;12(4):E545–E553. doi: 10.1055/a-2280-8277

Table 1 Demographic and clinical characteristics of the studied patients at time of first diagnosis.

Tx group NT group P value
*Close examination for gastrointestinal symptoms and other was unified and compared with medical check-up. †Excluding after ESD and after DG, chronic gastritis and no abnormal findings was compared. Tx, PPI/PCAB treatment; NT, no treatment; IQR, interquartile range; EGD, esophago-gastro-duodenoscopy; PPI, proton pump inhibitor; PCAB, potassium competitive acid blocker; EoE, eosinophilic esophagitis; EREFS, EoE endoscopic reference score; IEC, Intraepithelial eosinophil count; ESD, endoscopic submucosal dissection; DG, distal gastrectomy.
N 14 22 –
Male/female 12/2 19/3 1
Age at the first diagnosis, years, median (IQR) 52.5 (46.3–63.8) 45.5 (40.6–55) 0.26
Follow-up period, median, months (IQR) 84.5 (65.3–114.3) 92 (69.8–100) 0.99
Diffuse type/localized type 92.5 (60–114.3)/80.5 (72–116.8) 94 (84–98)/90 (69–100)
Number of follow-up EGDs, median (IQR) 7 (6–9.3) 7 (5–9) 0.67
Diffuse type/localized type 7 (5.5–9.3) / 7.5 (6.3–10.3) 8 (7–9) / 6 (5–9)
Initial PPI treatment (%) – 4 (18.2)
Opportunity for EE diagnosis

  • Medical check-up (%)

 11 (78.6) 19 (86.4) 0.6582 *

  • Close examination for gastrointestinal symptoms (%)

 2 (14.3) 0

  • Other (%)

 1 (7.1) 3 (13.6)
Allergic condition (%) 6 (42.9) 9 (40.9) 1

  • Allergic rhinitis

 5 (35.7) 8 (36.4) 1

  • Bronchial asthma

 1 (7.1) 1 (4.6) 1

  • Atopic dermatitis

 0 1 (4.6) 1

  • Food allergy

 0 0 –
Esophageal symptom (%) 7 (50) 3 (13.6) 0.0262
Dysphagia 4 (28.6) 1 (4.6) 0.0637
Food impaction 1 (7.1) 1 (4.6) 1
Heartburn 5 (35.7) 2 (9.1) 0.0842
EREFS score at first diagnosis, median (IQR)

  • Total score

 3 (2–5) 3 (3–4) 0.8243

  • Inflammatory score

 3 (2–3) 3 (2.75–3) 0.5101

  • Fibrostenotic score

 1 (0–1) 0 (0–1) 0.2503
Endoscopic phenotype (%)

  • Diffuse type

 10 (71.4) 7 (31.8) 0.0388

  • Localized type (lower esophagus type/patchy type)

 4 (3/1) (28.6) 15 (13/2) (68.2)
IEC at first diagnosis (/HFP, median (IQR)) 56 (30–79.3) 52.5 (27–70.5) 0.745
Background gastric mucosa (%)

  • Chronic gastritis

 3 (21.4) 10 (45.5) 0.2673 †

  • No abnormal findings

 9 (64.3) 10 (45.5)

  • After ESD/after DG

 0 (0)/2 (14.3) 2 (9)/(0) –
Successful H. pylori eradication after EoE diagnosis (%) 1 (8.3) 6 (30) 0.2117