Table 1.

Metabiotics related with microorganisms and their neurological properties.

Components	Microorganism	Health functional properties	References
Dopamine	Lactobacillus reuteri ATG-F4	Increase of cytokine IL-10 and serum dopamine level (AD)	[66]
Dopamine	Lactobacillus plantarum PS128	Reduction of motor dyskinesia and neurol apoptosis (PD)	[69]
Dopamine	Bifidobacterium bifidum, Bifidobacterium longum, Lactobacillus rhamnosus, Lactobacillus rhamnosus GG, Lactococcus lactis subsp. lactis, Lactobacillus plantarum LP28	Protection of dopamine-releasing neurons Decrease of motor dysfunctions	[71]
GABA	Lactobacillus sp., Bifidobacterium sp.	Reduction of anxiety and depression (anxiety and depression)	[53]
GABA	Lactobacillus rhamnosus JB-1	Alleviation of anxiety and depression by decreasing corticosterone (anxiety and depression)	[8]
GABA	Lactobacillus rhamnosus YS9	Control nerve	[57]
Histamine	Lactobacillus sp., Lactococcus sp., Enterococcus sp., Streptococcus sp., Escherichia sp.	Regulation of emotions Regulation of sleep and cognitive function (cognition)	[53]
Metabolites	Bacteroides fragilis NCTC 9343	Reduction of autistic behavior (AD)	[49]
Metabolites	Bifidobacterium breve A1	Reduction of neuroinflammation (AD)	[67]
SCFA	Lactobacillus rhamnosus, Lactobacillus reuteri, Bacterioides fragilis	Regulation of anti-inflammatory pathways (AD)	[53]
Serotonin	Lactobacillus sp. Lactococcus sp., Enterococcus sp., Streptococcus sp., Escherichia sp.	Regulation of emotions, sleep, and cognitive function (anxiety and depression, cognition)	[53]

GABA, gamma-amino butyric acid; SCFAs, short-chain fatty acids; AD, Alzheimer's disease; PD, Parkinson’s disease.