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. 2024 Mar 28;56(4):652–662. doi: 10.1038/s41588-024-01688-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 3 — (a) Denoised inferCNV output plot predicting copy number variation (CNV) profiles per cell over the epithelium of Donors 17 (left) and 37 (right), both containing the unique donor derived clusters (DDCs). Red (blue) indicates increased (decreased) expression in the respective genomic region. For each inferCNV test, a reference dataset of cells sampled from mammoplasty donors (excluding those tested) plus the remaining stroma/immune cells of the tested donor, were used to account for any cell type or donor specific expression profiles across the genome. (b) Similar analysis as above but for two randomly selected control mammoplasty donors.