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Analysis of the effect of age on IgG and IgM levels. Patients were divided into age groups with a 20-year interval and levels of IgG (A) and IgM (B) titers compared. One-way ANOVA with Bonferroni correction was used to assess differences in IgG and IgM levels between age groups. Significant differences are indicated by asterisks. *P < 0.05, **P < 0.01 and ***P < 0.001.
