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. 2024 Mar 28;6:63. Originally published 2023 Oct 20. [Version 2] doi: 10.12688/hrbopenres.13802.2

Table 1. Review Outcomes.

Primary Outcomes Perinatal Outcomes Umbilical artery pH less than 7.20
Umbilical artery pH less than 7.15
Umbilical artery pH less than 7.0
5 minute APGAR Score less than 7
Secondary Outcomes Umbilical artery base excess less then -10mmol/L
Umbilical artery lactate greater than 4.8 mmol/L
Correlation between FSp02 and umbilical artery and vein pH
Admission to NICU
Neonatal or intrapartum death
Cardiopulmonary resuscitation or intubation required within 24 hours of life
Hypoxic Ischaemic Encephalopathy
Umbilical vein oxygen saturation less than 55%
Low umbilical artery oxygen saturation less than 30%
Operative Delivery for Non-Reassuring Fetal Status (as defined by local
protocols in each study)
Operative Delivery for Dystocia
Fetal scalp pH <7.20
Fetal scalp lactate >4.8mmol/L
Long Term Outcomes Cerebral Palsy
Severe Neurodevelopmental Disability *

* Perinatal outcomes are defined as outcomes occurring within the first 24 hours of life.

** Severe neurodevelopmental disability was defined by a previous Cochrane review 39 ; “any one or a combination of the following: non‐ambulant cerebral palsy, developmental delay (developmental quotient less than 70), auditory and visual impairment assessed at 12 months of age or more. Development should have been assessed by means of a previously validated tool, such as Bayley Scales of Infant Development (Psychomotor Developmental Index and Mental Developmental Index” 40 .