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. 2024 Mar 26;4(4):100527. doi: 10.1016/j.xgen.2024.100527

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© 2024 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Using WGS data to assess the quality of the Liftover from Rnor_6.0 to mRatBN7.2

(A) Overview of the workflow using a real WGS sample from a WKY rat. A higher portion of variants passed the quality filter for mRatBN7.2. Among them, 97.93% of the variants were liftable from Rnor_6.0 to mRatBN7.2.

(B) The overlap between variants lifted from Rnor_6.0 and variants obtained by direct mapping sequence data to mRatBN7.2. Approximately 11.9% of the variants that were found from direct mapping were missing from the Liftover.