Table 2.

Sample intervention strategy for 4-dimensional variable grouping.

	KIOS logic pathway
Patient state	Anxiety: unchanged Depression: increased Agitation: decreased Difficulty sleeping: increased
Behavioral intervention taxonomy	2.2 Feedback on behavior 2.3 Self-monitoring of behavior 3.1 Social support 11.1 Pharmacological support 12.1 Restructuring the physical environment
Advice	“You’ve reported more difficulty sleeping and a rise in depression. Since these could be related, your first task is to work on sleep hygiene. Consider what you can adjust in your sleep environment to help you rest better at night. Can you reduce noise or light? Start dimming lights earlier in the evening? Do you need earplugs, or do you need to adjust room temperature? Brainstorm what might make you comfortable and restful and try changing up a few things in your sleep environment to help.” “Be sure you’re also following your medication guidelines. If things continue on a downward track, talk to your care provider or someone in your support system. It’s important to pay attention to depressive thoughts and to reach out for help if they don’t resolve.”