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. 2014 Jul 3;2014(7):CD009532. doi: 10.1002/14651858.CD009532.pub2

Comparison 11. Iron supplementation versus placebo/control: low risk of performance bias.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Deferral due to low haemoglobin (primary outcome) 3   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
1.1 Deferral at first donation visit after commencement of treatment 3 833 Risk Ratio (M‐H, Random, 95% CI) 0.29 [0.17, 0.50]
1.2 Deferral after multiple donation visits 2 541 Risk Ratio (M‐H, Random, 95% CI) 0.22 [0.11, 0.42]
1.3 Cumulative deferrals over multiple donation visits 3 1820 Risk Ratio (M‐H, Random, 95% CI) 0.25 [0.18, 0.35]
2 Haemoglobin (g/L) 3   Mean Difference (IV, Random, 95% CI) Subtotals only
2.1 Before further donation 3 270 Mean Difference (IV, Random, 95% CI) 4.76 [1.07, 8.45]
3 Serum ferritin (ng/mL) 3   Mean Difference (IV, Random, 95% CI) Subtotals only
3.1 Before further donation 3 594 Mean Difference (IV, Random, 95% CI) 13.31 [7.22, 19.40]