Figure 5.

Uterine leiomyosarcoma SKN cells were cultured in CytoSelect 48-well Cell Adhesion Assay plates, SFRP4 was added at a concentration of 2.5 µg/ml, and the absorbance was measured. The ‘0’ group was the SFRP4 untreated control group. (A) Adhesion ability of the leiomyosarcoma cells was significantly increased to each cell adhesion molecule (n=4). (B) A histological image comparing SFRP4-untreated cells and SFRP-treated (2.5 µg/ml) cells. An increase in cell number was observed in the treated group compared with the untreated group. Magnification, x40. ^*P<0.01 vs. control. Col, collagen; Lam, laminin I; SFRP, secreted frizzled-related protein.