Table II.
Expression of SFRP4 in different tissues.
| A, Expression of SFRP4 in normal uterine smooth muscle tissue | ||
|---|---|---|
| Tissue | Intensity | Proportion |
| Normal uterine smooth muscle 1 | 3 | 3 |
| Normal uterine smooth muscle 2 | 1 | 2 |
| Normal uterine smooth muscle 3 | 3 | 3 |
| Normal uterine smooth muscle 4 | 2 | 3 |
| B, Expression of SFRP4 in uterine fibroid tissue | ||
| Tissue | Intensity | Proportion |
| Uterine fibroid | 3 | 3 |
| Uterine fibroid 2 | 3 | 3 |
| Uterine fibroid 3 | 2 | 3 |
| Uterine fibroid 4 | 3 | 3 |
| C, Expression of SFRP4 in uterine leiomyosarcoma tissue | ||
| Tissue | Intensity | Proportion |
| Uterine leiomyosarcoma 1 | 1 | 1 |
| Uterine leiomyosarcoma 2 | 1 | 2 |
| Uterine leiomyosarcoma 3 | 1 | 1 |
| Uterine leiomyosarcoma 4 | 2 | 3 |
The expression of SFRP4 was assessed using immunostaining and evaluated based on the intensity and proportion scores. The median intensities and proportions of SFRP4 expression in uterine smooth muscle, fibroids and leiomyosarcomas were compared. SFRP4 expression in uterine leiomyosarcoma was significantly lower than that in normal uterine smooth muscle and uterine fibroids (n=4). P=0.01 vs. control. SFRP, secreted frizzled-related protein.