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. 2024 Mar 6;15(4):2175–2186. doi: 10.1364/BOE.515517

Fig. 1.

Fig. 1.

Processing pipeline. SIRENs will be used to create a motion-corrected and denoised microscopy stack from multiple repetitions of the same area. Subsequently, interplanes can be predicted with another SIREN model. Input data for the SIRENs are the spatial coordinates (x, y, z) of the image stacks, output values are the corresponding intensity values. SIREN-derived image quality is optionally further processed by a downstream denoiser network to improve spine recovery.