The statistics and difference of superficial and spatial features in Panc02-H7 MCTS. A, the normalized difference of selected features in the cross-statistical, cross-screening, and composite-hyperparameter. B, the absolute difference of selected features in the cross-statistical, cross-screening, and composite-hyperparameter. C, the representative images of the first two highest weight features of Panc02-H7 MCTS in the cross-statistical, cross-screening, and composite-hyperparameter. RMSE, root mean square error. D, the distribution of collagen within Panc02-H7 MCTS with different ratios of fibroblasts using confocal auto-fluorescence imaging. E, the comparison of collagen percentage within MCTS among different groups.