Table 6.
Prognostic factors for overall survival in the imatinib combined with hepatic resection group (IM+HR) and imatinib combined with radiofrequency ablation or transarterial chemoembolization group (IM+RFA/TACE) after propensity score matching.
Variables | Univariate HR (95% CI) | P | Multivariate HR (95% CI) | P |
---|---|---|---|---|
Sex (male vs. female) | 1.077 (0.197–5.902) | 0.932 | ||
Age (≤60 vs. >60 years) | 0.156 (0.025–0.954) | 0.044 | 0.119 (0.017–0.856) | 0.035 |
Primary Sites (stomach vs. others) | 1.032 (0.328–8.123) | 0.550 | ||
Metastatic phase (metachronous vs. synchronous) | 0.466 (0.084–2.602) | 0.384 | ||
Number of Metastases (≤3 vs. >3) | 0.199 (0.023–1.709) | 0.141 | ||
Largest diameter of metastases (≤3 vs. >3 cm) | 0.802 (0.162–3.979) | 0.781 | ||
Extrahepatic metastases (no vs. yes) | 0.377 (0.068–2.081) | 0.263 | ||
IM response before surgical treatment (PR+SD+NA vs. PD) | 0.476 (0.095–2.388) | 0.367 | ||
Status after surgical treatment (NED vs. non-NED) | 0.150 (0.017–1.295) | 0.084 | 0.122 (0.013–1.136) | 0.065 |
Therapy (IM+HR vs. IM+RFA/TACE) | 0.182 (0.021–1.560) | 0.120 |
HR, hazard ratio.
NA, not applicable; NED, no evidence of disease; PD, progressive disease; PR, partial response; SD, stable disease.