Table 2.

Female representation and outcomes in landmark RCTs on management of patients in cardiogenic shock

Study name	Year	Intervention	Indication	n	Women (%)	Main outcomes in women compared to men
IABP-SHOCK II68	2012	IABP vs. no IABP	AMI-CS	600	31	Consistent results in men and women with respect to 30-day mortality
CULPRIT-SHOCK66,67	2017	Culprit-lesion-only vs. multivessel PCI	AMI-CS	686	24	No interaction between sex and coronary revascularization strategy regarding mortality or renal failure (interaction P = 0.11)
ECLS-SHOCK69	2023	ECLS vs. no ECLS	AMI-CS	420	19	Consistent results in men and women with respect to 30-day mortality

AMI-CS, acute myocardial infarction-cardiogenic shock; ECLS, extracorporeal life support; IABP, intra-aortic balloon pump; PCI, percutaneous coronary intervention; RCT, randomized controlled trial.