Table 1. Hepatotoxicity in HIV-infected children and adolescents on antiretroviral therapy, in relation to gender, viral load and classification. Data were collected from March 2003 to April 2004 in a university hospital.
| Hepatotoxicity | |||
|---|---|---|---|
| Yes | No | OR (95% CI) | |
| Gender | |||
| Male | 13 | 69 | 1.70 (0.76-3.81) |
| Female | 17 | 53 | |
| Viral load (copies/ml) | |||
| > 100,000 | 3 | 2 | 6.66 (1.06-41.85) |
| < 100,000 | 27 | 120 | |
| Immunological category | |||
| 1 | 5 | 19 | 1.00 |
| 2 | 8 | 61 | 0.49 (0.14-1.70) |
| 3 | 17 | 42 | 1.53 (0.49-4.78) |
| Clinical category | |||
| N + A | 5 | 30 | 1.00 |
| B | 13 | 65 | 1.19 (0.39-3.67) |
| C | 12 | 27 | 2.66 (0.83-8.54) |
OR = odds ratio; CI = confidence interval; N = asymptomatic; A = mildly symptomatic; B = moderately symptomatic; C = severely symptomatic.