Table 4.
Four clinical models: the strategy of selecting the best scale of variables
| Method | Clinical Model | Integrated Brier Score | Prediction Error | C-index | AUC (CI) |
|---|---|---|---|---|---|
| Cox-PH | 1 | 0.011 | 0.011 | 90.03 | 93.83 (93.12–94.54) |
| 2 | 0.011 | 0.012 | 90.21 | 93.42 (92.71–94.13) | |
| 3 | 0.011 | 0.011 | 91.47 | 93.48 (92.77–94.19) | |
| 4 | 0.011 | 0.012 | 88.06 | 91.97 (91.26–92.68) | |
| GBM | 1 | 0.013 | 0.013 | 89.79 | 90.52 (89.81–91.23) |
| 2 | 0.013 | 0.013 | 90.14 | 91.14 (90.43–91.85) | |
| 3 | 0.013 | 0.013 | 90.18 | 91.67 (90.96–92.38) | |
| 4 | 0.013 | 0.013 | 86.52 | 87.25 (86.54–87.96) | |
| SVM | 1 | 0.014 | 0.013 | 75.99 | 85.25 (84.54–85.96) |
| 2 | 0.014 | 0.013 | 89.10 | 90.01 (89.30–90.72) | |
| 3 | 0.014 | 0.013 | 89.63 | 90.13 (89.42–90.84) | |
| 4 | 0.014 | 0.013 | 88.95 | 89.95 (89.24–90.66) | |
| SL | 1 | 0.011 | 0.011 | 91.60 | 94.34 (93.63–95.05) |
| 2 | 0.011 | 0.011 | 90.55 | 93.59 (92.88–94.30) | |
| 3 | 0.011 | 0.011 | 92.81 | 93.73 (93.02–94.44) | |
| 4 | 0.012 | 0.011 | 87.97 | 91.86 (91.15–92.57) |
Model I included Age, Sex, Smoking status, Education, Marital Status, Family History of Stroke, SBP, DBP, BMI, Waist, Hip, FBS, TG, HDL, Physical Activity, Lipid Drug, Anti-Hypertension Drug, Aspirin, Corticosteroid; Model III included Age, Sex, Smoking, Education, Marital Status, Family History of Stroke, Anti-Hypertension Drug, BMI categorization, Waist-to-Hip Ratio, T2DM, high TG, low HDL, and Physical Activity. GBM = Gradient boosting model; SVM = support vector model; SL = super learner; CI confidence interval