Table 3.
ID | CINV prophylaxis during treatment* | CINV rescue medication | CINV symptoms during treatment** | CINV score*** | |||
---|---|---|---|---|---|---|---|
Nausea | Vomiting | Appetite/intake | Weight loss | ||||
1 | No | - | - | - | - | 0 | |
2 | No | n.a. | n.a. | - | - | 0 | |
3 | 1 | ± | ± | + | - | 2 | |
4 | 1 | + + | + + | n.a. | n.a. | 4 | |
5 | 1 | + | - | + | + | 3 | |
6 | 1 | MCP 0.5 mg/kg/day | + + | + + | ± | + | 5 |
7 | 1 | - | + | n.a. | - | 1 | |
8 | 1 | + + | + + | ± | + | 5 | |
9 | 1 | + | - | - | - | 1 | |
10 | 1 | + + | + | - | - | 3 | |
11 | 1 | + + | + | + | - | 4 | |
12 | 2 | ± | ± | ± | ± | 2 | |
13 | 3 | + | ± | ± | + | 3 | |
14 | 3 | MCP 0.6 mg/kg/day | + + | + + | + | - | 5 |
15 | 3 | + | + | + | + | 4 | |
16 | 3 | + + | - | - | - | 2 | |
17 | 3 | - | ± | ± | + | 2 |
MCP metoclopramide
*1, 5-HT3 receptor antagonist; 2, 5-HT3 receptor antagonist + dexamethasone; 3, 5-HT3 receptor antagonist + (fos)aprepitant +/- dexamethasone
**- none, ± mild, + moderate, + + severe, n.a. not available
***CINV score 0 and 1, none to mild; 2 and 3, moderate; 4 and 5, severe. Based on CINV symptoms during treatment, CINV prophylaxis during treatment, and score of primary care provider