Table 1.
Demographic characteristics of the study OA population stratified by CMCOI status
| CCAE | MDCR | Optum CDM | |||||||
|---|---|---|---|---|---|---|---|---|---|
| No CMCOI | CMCOIa | Total | No CMCOI | CMCOI | Total | No CMCOI | CMCOI | Total | |
| n | 3,695,622 | 3,406,452 | 7,102,074 | 706,321 | 2,052,400 | 2,758,721 | 2,509,846 | 5,471,987 | 7,981,833 |
| % OA population | 52.0% | 48.0% | 100.0% | 25.6% | 74.4% | 100.0% | 31.4% | 68.6% | 100.0% |
| Age, mean (SD), years | 50.7 (10.3) | 55.0 (7.9) | 52.8 (9.5) | 73.7 (7.2) | 75.9 (7.9) | 75.4 (7.8) | 56.6 (14.2) | 67.9 (12.3) | 64.4 (14.0) |
| 18–24 | 1.9% | 0.4% | 1.1% | 0% | 0% | 0% | 1.3% | 0.1% | 0.5% |
| 25–44 | 20.4% | 9.6% | 15.2% | 0.0% | 0.0% | 0.0% | 17.1% | 3.8% | 8.0% |
| 45–64 | 75.2% | 86.7% | 80.7% | 1.9% | 1.6% | 1.7% | 49.6% | 31.1% | 36.9% |
| 65–79 | 1.6% | 3.2% | 2.4% | 77.2% | 66.2% | 69.0% | 26.8% | 46.6% | 40.4% |
| ≥80 | 0% | 0.0% | 0.0% | 20.9% | 32.2% | 29.3% | 4.6% | 18.3% | 14.0% |
| Female | 59.0% | 56.1% | 57.6% | 64.6% | 59.8% | 61.0% | 59.2% | 59.2% | 59.2% |
CCAE IBM MarketScan Commercial Database, CMCOI coexisting medical conditions of interest, MDCR IBM MarketScan Medicare Supplemental Database, OA osteoarthritis, Optum CDM Optum’s de-identified Clinformatics® Data Mart Database, SD standard deviation
aThe CMCOI population refers to those patients observed to have one or more of cardiovascular risk, gastrointestinal bleeding risk, asthma, or renal impairment present