Concentrations of MPs in human thrombi from different vascular locations. (a) Concentrations of total MPs in the AC (n = 10) and PC (n = 3) of the IS group. (b–d) Concentrations of PA66, PVC, and PE in the AC (n = 10) and PC (n = 3) of the IS group. Unpaired t-test, ∗∗p < 0.01. (e) Concentrations of MPs in the proximal (n = 3) and distal (n = 7) AC. Mann–Whitney U test, ∗p < 0.05. (f) NIHSS score, which reflects stroke severity, of patients with IS with low (n = 7) or high (n = 6) levels of MPs. Unpaired t-test, ∗p < 0.05. (g) Concentrations of MPs in the proximal (n = 2) and distal (n = 7) veins of DVT samples. Unpaired t-test, ∗p < 0.05. (h) Concentrations of MPs in arterial (n = 15) and venous (n = 9) thrombotic diseases. Abbreviations: AC, anterior circulation; PC, posterior circulation; NIHSS, National Institutes of Health Stroke Scale.