Table 2:
Cox proportional hazards multivariate model examining factors associated with overall survival in soft tissue sarcoma SCARE histologies
| Characteristic* | HR (95% CI) | P-Value |
|---|---|---|
|
| ||
| Histology | ||
| Synovial | Ref | |
| Clear cell | 1.98 (1.56,2.52) | <0.001 |
| Angiosarcoma | 2.23 (1.90,2.63) | <0.001 |
| Rhabdomyosarcoma | 1.46 (1.22,1.76) | <0.001 |
| Epithelioid | 1.27 (1.04,1.55) | 0.018 |
| Regional Lymph Node Status | ||
| No RLNS | Ref | |
| Negative RLN | 0.84 (0.7,1.02) | 0.072 |
| Positive RLN | 2.45 (1.64,3.64) | <0.001 |
| Age | ||
| <18 years | Ref | |
| 18 – 39 years | 1.81 (1.34,2.45) | <0.001 |
| 40 – 64 years | 2.60 (1.93,3.48) | <0.001 |
| >=65 years | 5.63 (4.12,7.69) | <0.001 |
| Male vs Female | 1.27 (1.13,1.42) | <0.001 |
| White vs Nonwhite | 0.93 (0.81,1.08) | 0.35 |
| 0 vs >0 Comorbidities | 0.79 (0.68,0.91) | 0.001 |
| Poorly/Undifferentiated | ||
| No | Ref | <0.001 |
| Yes | 1.97 (1.55,2.51) | <0.001 |
| Unknown | 1.67 (1.33,2.10) | <0.001 |
RLNS: Regional lymph node surgery; RLN: Regional lymph node;
*
Tumor size, receipt of chemotherapy, and receipt of radiation therapy violated the proportional hazards assumption and these results are stratified on those variables