Fig. 1.

Schematic diagram of different microextraction methods of tyrosine kinase inhibitors (TKIs): (A) salting-out-assisted switchable hydrophilicity solvent-based liquid-phase microextraction (SA-SHS-LPME), (B) stirring-controlled solidified floating solid-liquid drop microextraction (SC-SF-SLDME), (C) dispersive microsolid-phase extraction (D-μ-SPE) [54], and (D) hollow-fiber solid-phase microextraction (HF-SPME). UPLC: ultra-performance liquid chromatography tandem mass spectrometry. Reprinted from Ref. [54] with permission.