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. Author manuscript; available in PMC: 2024 Apr 17.
Published in final edited form as: J Am Chem Soc. 2023 Sep 8;145(37):20634–20645. doi: 10.1021/jacs.3c07849

Figure 1.

Figure 1.

Fusicoccanes such as cotylenin A function as molecular glues between 14-3-3 proteins and phosphoprotein clients (from PDB: 4IHL, ref. 4a). C-RAFpp = diphosphorylated C-RAF peptide.