Figure 1: β-Aminopropionitrile (BAPN) treatment increases swine abdominal aortic aneurysm (AAA) size.
(A) BAPN + surgery/elastase swine had significantly higher mean aortic dilation compared with non-BAPN-treated (surgery/elastase alone) swine at 28 days (113.5% ± 30.2% vs. 59.7% ± 29.2%; P < .01). (B) BAPN-treated swine showed mean aortic dilation of 86.9% ± 47.4%, 105.4% ± 58.1%, and 113.5% ± 30.2% at 7, 14, and 28-day harvest time points, respectively. This figure was published by Cullen et al.15 and reproduced here with permission.