Table 3.

Long-term outcomes of included studies

Author	Median DFS (months)	Median overall survival (months)	QOL outcomes
Portillaet al. [15]		20	.
Glehenet al. [25]	.	57.6 &	.
Bijelicet al. [26]	.	39	.
Bretcha-Boixet al. [27]	.	> 18 m	.
Cashinet al. [28]		23 (R 9–98)	.
Votanopouloset al. [29]	.	55.7 (R 0.3-110.2)	.
Chuaet al. [30]	.	23 (R 16.9–28.3)	.
Williamset al. [31]		22.6	.
Choudryet al. [23]	9.1 (R 3.9–14.3)	.	.
Jostet al. [32]	.	40 m (SD 12)	.
Lakset al. [24]	8.7 (R 1.2–26.3)	.	.
Paaschet al. [33]		R 16–87	.
Suttonet al. [18]		62.6 (R 25.3–99.9)	.
Valenzuelaet al. [34]	.	40.1	.
Pasqualet al. [35]	.	21 #	.

DFS = disease free survival.

QOL = quality of life.

R = range.

m = mean, SD = standard deviation.

& = from initial CRS procedure.

# calculated using Kaplan-Meier survival analysis