TABLE 1.
Comparisons of amino acid and nucleic acid homologies of Aichi virus with representatives of other picornaviruses
| Region | No. of amino acid or RNA residues (% homology)
|
||||||
|---|---|---|---|---|---|---|---|
| Aichi | PV1 | HRV2 | EMCV | FMDV-O | HAV | E22 | |
| 5′ NTR | 712 | 742 (47) | 610 (48) | 833 (45) | 713 (48) | 735 (48) | 709 (46) |
| L | 170 | —a | — | 67 (14) | 217 (18) | 6 (2) | 12 (4) |
| VP0 | 371 | 341 (22) | 330 (21) | 326 (23) | 287 (25) | 239 (19) | 289 (20) |
| VP3 | 223 | 238 (27) | 237 (27) | 231 (32) | 220 (23) | 246 (21) | 253 (24) |
| VP1 | 278 | 302 (23) | 289 (23) | 277 (23) | 213 (19) | 300 (19) | 234 (20) |
| 2A | 111 | 149 (18) | 136 (19) | 143 (15) | 16 (5) | 189 (20) | 147 (20) |
| 2B | 165 | 97 (18) | 95 (15) | 150 (21) | 154 (24) | 107 (20) | 122 (18) |
| 2C | 335 | 329 (28) | 322 (27) | 325 (30) | 318 (32) | 335 (29) | 329 (28) |
| 3A | 95 | 87 (22) | 77 (20) | 88 (17) | 153 (17) | 74 (17) | 117 (20) |
| 3B (VPg) | 27 | 22 (32) | 21 (33) | 20 (19) | 23/24 (19/28)b | 23 (22) | 20 (30) |
| 3C | 190 | 183 (24) | 183 (25) | 205 (23) | 213 (22) | 219 (24) | 200 (17) |
| 3D | 468 | 461 (36) | 460 (32) | 460 (35) | 470 (36) | 489 (26) | 469 (27) |
| 3′ NTR | 240 | 71 (21) | 42 (12) | 126 (30) | 95 (25) | 63 (18) | 90 (23) |
a
—, no leader protein is encoded.
b
Three VPg’s in tandem are encoded, each with 23 or 24 aa.