1 Successful discontinuation of BZDs |
11 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
1.1 Post treatment |
9 |
423 |
Risk Ratio (M‐H, Random, 95% CI) |
1.40 [1.05, 1.86] |
1.2 3 month follow‐up |
9 |
460 |
Risk Ratio (M‐H, Random, 95% CI) |
1.51 [1.15, 1.98] |
1.3 6 month follow‐up |
3 |
155 |
Risk Ratio (M‐H, Random, 95% CI) |
1.94 [0.88, 4.30] |
1.4 11/12 month follow‐up |
5 |
284 |
Risk Ratio (M‐H, Random, 95% CI) |
1.42 [0.89, 2.28] |
1.5 15 month follow‐up |
1 |
146 |
Risk Ratio (M‐H, Random, 95% CI) |
0.8 [0.49, 1.31] |
1.6 Follow‐up ≥ 24 months |
2 |
73 |
Risk Ratio (M‐H, Random, 95% CI) |
1.77 [0.98, 3.17] |
2 Sensitivity analysis (Allocation concealment): successful discontinuation of BZDs |
8 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
2.1 Post treatment |
8 |
370 |
Risk Ratio (M‐H, Random, 95% CI) |
1.50 [1.12, 2.02] |
3 Sensitivity analysis (Blinding of assessor): successful discontinuation of BZDs |
5 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
3.1 Post treatment |
4 |
159 |
Risk Ratio (M‐H, Random, 95% CI) |
1.08 [0.73, 1.59] |
3.2 3 month follow‐up |
4 |
103 |
Risk Ratio (M‐H, Random, 95% CI) |
1.60 [1.08, 2.36] |
3.3 6 month follow‐up |
2 |
94 |
Risk Ratio (M‐H, Random, 95% CI) |
1.98 [0.37, 10.47] |
3.4 12 month follow‐up |
1 |
62 |
Risk Ratio (M‐H, Random, 95% CI) |
0.70 [0.28, 1.79] |
3.5 Follow‐up ≥ 24 months |
1 |
21 |
Risk Ratio (M‐H, Random, 95% CI) |
2.73 [1.02, 7.32] |
4 Reduce BZDs > 50% |
4 |
|
Odds Ratio (M‐H, Random, 95% CI) |
Subtotals only |
4.1 Post treatment |
3 |
178 |
Odds Ratio (M‐H, Random, 95% CI) |
0.93 [0.11, 8.18] |
4.2 3 month follow‐up |
2 |
69 |
Odds Ratio (M‐H, Random, 95% CI) |
1.99 [0.47, 8.47] |
4.3 6 month follow‐up |
1 |
62 |
Odds Ratio (M‐H, Random, 95% CI) |
0.76 [0.28, 2.07] |
4.4 12 month follow‐up |
2 |
125 |
Odds Ratio (M‐H, Random, 95% CI) |
1.07 [0.14, 8.21] |
5 Drop‐outs or lost to follow‐up |
10 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
5.1 From 0 to post treatment follow‐up |
9 |
478 |
Risk Ratio (M‐H, Random, 95% CI) |
1.05 [0.66, 1.66] |
5.2 From 0 to 3 month follow‐up |
1 |
65 |
Risk Ratio (M‐H, Random, 95% CI) |
1.71 [0.16, 17.98] |
5.3 From 0 to 6 month follow‐up |
1 |
62 |
Risk Ratio (M‐H, Random, 95% CI) |
0.70 [0.17, 2.88] |
5.4 From 0 to 12 month follow‐up |
1 |
65 |
Risk Ratio (M‐H, Random, 95% CI) |
2.57 [0.28, 23.44] |