Study	Reason for exclusion
Adel 2010	Quasi‐randomised clinical trial (n = 37) assessing effects of IV pentoxifylline versus placebo on coagulation in neonates with sepsis. Excluded because a) study participants were predominantly term and late preterm neonates and b) respiratory outcomes were not reported. Outcomes of this trial are reported in another systematic review (Haque 2011).
Ali 2006	Randomised clinical trial (n = 50) assessing effects of IV pentoxifylline versus placebo in neonates with sepsis. Excluded because gestational age range of participants was 32 to 37 weeks. Outcomes of this trial are reported in another systematic review (Haque 2011).
Lauterbach 1996	Randomised clinical trial (n = 40) assessing effects of IV pentoxifylline versus placebo in preterm neonates < 36 weeks gestational age with sepsis. Excluded because a) gestational age of a significant proportion of participants was > 32 weeks and b) respiratory outcomes were not reported. Outcomes of this trial are reported in another systematic review (Haque 2011).
Lauterbach 1999	Case series describing the use of nebulised pentoxifylline in five preterm neonates with established BPD. Excluded because the study was not a randomised or quasi‐randomised trial.
Lauterbach 1999a	Randomised clinical trial (n = 100) assessing effects of IV pentoxifylline versus placebo in preterm neonates < 36 weeks gestational age with late‐onset sepsis. Excluded because a) gestational age of a significant proportion of participants was > 32 weeks and b) respiratory outcomes were not reported. Outcomes of this trial are reported in another systematic review (Haque 2011).