Table 1.
Total, N | 13 |
Age at Diagnosis- yr: Median(Range) | 62 (44–75) |
Gleason score- no. (%) | |
7 | 4 (31) |
8 | 1 (8) |
9 | 4 (31) |
10 | 1 (8) |
Unknown | 3 (23) |
De Novo Amphicrine Disease, no. (%) | 5 (38) |
Treatment-Emergent Amphicrine Disease, no. (%) | 8 (62) |
Presented with metastatic disease at diagnosis (%) | 5 (38) |
Use of standard ADT no. (%) | 13 (100) |
Use of abiraterone, no. (%) | 7 (54) |
Use of enzalutamide, no. (%) | 4 (31) |
Use of docetaxel, no. (%) | 7 (54) |
Use of cabazitaxel, no. (%) | 1 (8) |
Use of taxane + platinum chemotherapy, no. (%) | 4 (31) |
Use of sipeleucel-T, no. (%) | 3 (23) |
Use of radium-223, no. (%) | 1 (8) |
Clinical Trial Participation, no. (%)* | 4 (31) |
Clinical Trials: Phase I Taiho TO-TASS3681–101 (NCT02566772) (Pt 2), Phase I DuoBody PSMA bispecific antibody (NCT03926013) (Pt 2), Phase II BAT + Olaparib (NCT03516812) (Pt 4), Phase II Bipolar Androgen Therapy (NCT02286921) (Pt 7), Inovio DNA Vaccine (NCT02514213) (Pt 14)