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. 2024 Apr 17;8(2):e194–e201. doi: 10.1055/s-0044-1785525

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The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ )

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 2 — Stabilization and treatment of the patient. *Hemodynamic instability defined by shock index (heart rate/systolic blood pressure) >1. **Locations requiring rapid action: head and neck bleeding, compartment syndrome, central nervous system, gastrointestinal, major surgery, and major trauma, among others. aPCC, activated prothrombin complex concentrate; FVIII, coagulation factor VIII; rFVIIa, recombinant activated factor VII.