Table 1.
Mean intake of food/water as well as initial and final body weight in rats and rabbits following 180 days of administration.
| Animal | Sex | Group | N | Initial weight (g) | Final weight (g) | Body weight gain∗ (g) | Food (g) | Water (mL) |
|---|---|---|---|---|---|---|---|---|
| Rats | Females | Test | 5 | 195.33 ± 7.16 | 265.38 ± 17.17∗∗∗ | 68.12 ± 18.48∗∗∗ | 16.5 ± 3.9 | 29.2 ± 5.7 |
| Control | 5 | 191.69 ± 5.49 | 251.54 ± 20.60 | 59.85 ± 20.22 | 15.3 ± 2.0 | 26.1 ± 12.2 | ||
| p value | 0.39 | 0.37 | 0.59 | 0.49 | 0.64 | |||
| Males | Test | 5 | 316.52 ± 18.54 | 545.90 ± 37.33∗∗∗ | 218.47 ± 30.56∗∗∗ | 24.0 ± 10.5 | 37.5 ± 4.2 | |
| Control | 5 | 317.28 ± 18.85 | 510.10 ± 38.26 | 192.82 ± 25.92 | 28.0 ± 3.3 | 37.5 ± 4.2 | ||
| p value | 0.95 | 0.24 | 0.25 | 0.51 | 0.60 | |||
|
| ||||||||
| Rabbits | Females | Test | 5 | 2998 ± 94.12 | 5027 ± 631.30∗∗∗ | 2029 ± 537.19∗∗∗ | 163.5 ± 68.9 | 248.8 ± 158.5 |
| Control | 5 | 3258 ± 299.74 | 5848 ± 65.05∗∗ | 2590 ± 234.70∗∗ | 177 ± 33.9 | 260.0 ± 146.7 | ||
| p value | 0.10 | 0.18 | 0.65 | 0.67 | 0.89 | |||
| Males | Test | 5 | 2903 ± 318.58 | 4221 ± 419.53∗∗∗∗ | 1317.40 ± 100.95∗∗∗∗ | 180.6 ± 48.6 | 324.3 ± 165.9 | |
| Control | 5 | 2937 ± 221.26 | 4538 ± 292.40∗∗∗ | 1601.07 ± 71.14∗∗∗ | 140.8 ± 46.7 | 236.0 ± 137.0 | ||
| p value | 0.85 | 0.32 | 0.73 | 0.19 | 0.35 | |||
N: number of animals in the group, data expressed as mean ± standard deviation. ∗Body weight gain = initial weight–final weight. Number of animals per group at the end of the experiment: ∗∗N = 2, ∗∗∗N = 3, ∗∗∗∗N = 4.