Table 3.
Effects of P2Et extract on biochemical parameters in rats following 180 days of administration.
| Parameters (reference values) | Group | p value | ||
|---|---|---|---|---|
| Test (N = 6) | Control (N = 8) | |||
| Kidney function | Urea (18.0 to 45.0 mg/dL) | 47.30 ± 5.91 | 57.41 ± 6.29 | 0.01∗ |
| Creatinine (0.05 to 0.65 mg/dL) | 0.40 ± 0.09 | 0.38 ± 0.05 | 0.54 | |
| Sodium (135.0 to 146.0 mmol/L) | 148.95 ± 8.82 | 153.99 ± 21.17 | 0.52 | |
| Potassium (4.0 to 5.9 mmol/L) | 7.95 ± 2.20 | 6.16 ± 0.77 | 0.05∗ | |
| Chloride (96.0 to 107.0 mmol/L) | 100.30 ± 1.11 | 99.76 ± 2.26 | 0.60 | |
| Calcium (5.3 to 11.6 mg/dL) | 10.97 ± 0.93 | 10.28 ± 0.59 | 0.12 | |
|
| ||||
| Liver function | ALT (20 to 61 U/L) | 83.00 ± 39.59 | 95.13 ± 30.98 | 0.12 |
| Phosphatase (16 to 302 U/L) | 190.33 ± 55.32 | 249.75 ± 59.88 | 0.08 | |
| AST (39.0 to 111.0 U/L) | 199.17 ± 153.83 | 213.88 ± 55.98 | 0.16 | |
| GGT (0 to 6 U/L) | 5.00 ± 0.00 | 4.88 ± 0.35 | 0.70 | |
| Bilirubin (0.1 to 0.7 mg/dL) | 0.17 ± 0.18 | 0.10 ± 0.00 | 0.61 | |
| Cholesterol (20 to 92 mg/dL) | 53.00 ± 10.79 | 50.13 ± 6.06 | 0.70 | |
| Triglycerides (27 to 108 mg/dL) | 164.60 ± 48.70 | 130.29 ± 52.37 | 0.24 | |
N: number of animals in the group, data expressed as mean ± standard deviation. ∗Statistically significant difference p < 0.05. ALT: alanine transaminase); AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase.