Table 4.
Effects of P2Et extract on hematological parameters in rats following 180 days of administration.
| Parameters (reference values) | Group | p value | ||
|---|---|---|---|---|
| Test (N = 6) | Control (N = 8) | |||
| Erythrogram | Erythrocyte (6.6 to 9.0 million/mm3) | 6.62 ± 0.21 | 6.71 ± 0.52 | 0.69 |
| Hemoglobin (13.2 to 16.4 g/dL) | 14.43 ± 0.51 | 14.08 ± 0.83 | 0.37 | |
| Hematocrit (41.1 to 51.1%) | 43.87 ± 2.12 | 43.25 ± 2.60 | 0.56 | |
| MCV (52.5 to 65.4 μ3) | 66.33 ± 4.32 | 64.54 ± 2.41 | 0.34 | |
| MCH (16.5 to 21.3 pg) | 21.83 ± 0.85 | 21.01 ± 0.93 | 0.12 | |
| MCHC (30.2 to 34.5 g/dL) | 32.93 ± 1.07 | 32.58 ± 0.84 | 0.49 | |
|
| ||||
| Leucogram | Leukocytes (7.3 to 12.6 thousands/mm3) | 5.52 ± 1.61 | 6.14 ± 1.33 | 0.44 |
| Neutrophil (28 to 44%) | 39.17 ± 7.55 | 37.88 ± 3.94 | 0.68 | |
| Eosinophil (1 to 5%) | 0.67 ± 0.82 | 0.50 ± 0.76 | 0.70 | |
| Lymphocytes (39 to 72%) | 57.83 ± 7.36 | 59.13 ± 3.80 | 0.68 | |
| Monocytes (3 to 12%) | 2.33 ± 1.21 | 2.50 ± 1.20 | 0.80 | |
|
| ||||
| Coagulogram | PT (seconds) | 16.94 ± 1.50 | 16.14 ± 0.63 | 0.20 |
| Platelets (0.84 to 1.24 million/mm3) | 0.73 ± 0.16 | 0.73 ± 0.14 | 0.99 | |
| PPT (seconds) | 21.16 ± 4.36 | 25.84 ± 4.51 | 0.09 | |
|
| ||||
| Total protein | 6.8 to 8.7 g/dL | 7.00 ± 0.22 | 7.13 ± 0.38 | 0.49 |
N: number of animals in the group, data expressed as mean ± standard deviation. MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration (MCHC); PT: prothrombin time; PPT: partial thromboplastin time.