Table 5.
Effects of P2Et extract on hematological parameters in rabbits following 180 days of administration.
| Parameters and reference values | Group | p value | ||
|---|---|---|---|---|
| Test (N = 7) | Control (N = 5) | |||
| Erythrogram | Erythrocytes (5.1 to 7.9 million/mm3) | 6.07 ± 0.34 | 5.65 ± 0.39 | 0.08∗ |
| Hemoglobin (10.0 to 17.4 g/dL) | 13.34 ± 0.71 | 12.24 ± 0.52 | 0.02 | |
| Hematocrit (33.0 to 50.0%) | 38.11 ± 2.24 | 36.18 ± 2.01 | 0.16 | |
| MVC (57.8 to 66.5 μ3) | 62.80 ± 0.99 | 64.24 ± 5.37 | 0.87 | |
| MHC (17.1 to 23.5 pg) | 21.99 ± 0.35 | 21.68 ± 1.06 | 0.49 | |
| MCHC (29.0 to 37.0 g/dL) | 35.03 ± 0.43 | 33.86 ± 1.47 | 0.10 | |
|
| ||||
| Leucogram | Leukocytes (5.2 to 12.5 thousands/mm3) | 7.34 ± 1.64 | 6.18 ± 2.34 | 0.33 |
| Neutrophil (20 to 75%) | 56.29 ± 9.62 | 44.60 ± 8.62 | 0.06 | |
| Eosinophil (1 to 4%) | 0.43 ± 0.53 | 1.40 ± 1.52 | 0.19 | |
| Lymphocytes (30 to 85%) | 39.43 ± 9.36 | 52.40 ± 7.60 | 0.03 | |
| Monocytes (1 to 4%) | 3.86 ± 3.08 | 1.60 ± 0.89 | 0.11 | |
|
| ||||
| Coagulogram | PT (7.2 to 7.8 seconds) | 6.29 ± 0.26 | 6.72 ± 0.65 | 0.14 |
| Platelets (250 to 650 thousands/mm3) | 382.71 ± 116.43 | 271.60 ± 36.79 | 0.05 | |
| PTT (35 seconds) | 19.29 ± 1.95 | 16.86 ± 0.65 | 0.02∗ | |
|
| ||||
| Total protein | 5.4 to 8.5 g/dL | 6.11 ± 0.28 | 6.12 ± 0.44 | 0.38 |
N: number of animals in the group, data expressed as mean ± standard deviation. ∗Statistically significant difference p < 0.05. MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration (MCHC); PT: prothrombin time; PPT: partial thromboplastin time.