Table 6.
Effects of P2Et extract on biochemical parameters in rabbits following 180 days of administration.
| Parameters and reference values | Group | p value | ||
|---|---|---|---|---|
| Test (N = 7) | Control (N = 5) | |||
| Kidney function | Urea (13.0 to 52.0 mg/dL) | 51.37 ± 12.83 | 48.50 ± 6.76 | 0.66 |
| Creatinine (0.80 to 1.80 mg/dL) | 1.28 ± 0.29 | 1.27 ± 0.15 | 0.91 | |
| Sodium (138.0 to 148.0 mmol/L) | 146.20 ± 2.13 | 146.30 ± 1.81 | 0.93 | |
| Potassium (3.3 to 6.9 mmol/L) | 4.84 ± 0.27 | 4.76 ± 0.17 | 0.55 | |
| Chloride (92.0 to 112.0 mmol/L) | 99.04 ± 2.84 | 101.36 ± 2.50 | 0.17 | |
| Calcium (5.6 to 12.0 mg/dL) | 12.17 ± 0.35 | 12.62 ± 0.74 | 0.19 | |
|
| ||||
| Liver function | ALT (31 to 60 U/L) | 81.43 ± 17.90 | 88.00 ± 26.23 | 0.62 |
| Phosphatase (90 to 145 U/L) | 36.14 ± 5.58 | 45.40 ± 27.49 | 0.50 | |
| AST (42.0 to 98.0 U/L) | 28.86 ± 7.20 | 31.40 ± 11.93 | 0.65 | |
| GGT (4 to 12 U/L) | 5.86 ± 1.46 | 5.40 ± 0.55 | 0.81 | |
| Bilirubin (0.30 to 0.80 mg/dL) | 0.30 ± 0.08 | 0.23 ± 0.11 | 0.23 | |
| Cholesterol (35 to 60 mg/dL) | 45.00 ± 0.00 | 47.20 ± 3.90 | 0.26 | |
| Triglycerides (124 to 156 mg/dL) | 48.76 ± 5.59 | 55.48 ± 20.56 | 0.81 | |
N: number of animals in the group, data expressed as mean ± standard deviation. ALT: alanine transaminase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase.