Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Apr 12;19:3537–3554. doi: 10.2147/IJN.S451589

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 Broering et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Histopathological sections performed with HE dyes. (A) Histopathological score represented by arbitrary units. The sections were blindly evaluated and considered alterations were highlighted. Tissue edema (square brackets), inflammatory infiltrates (black arrow head) and ulcerations (red arrow). Naïve section presenting normal histoarchitecture. Mice colon sections submitted to IHC. (B) Representative sections and percentage (%) of marked area for Claudin-1 marker. Black square represents the apical region. (C) Representative sections and, number of positive cells per field for MUC-2 marker. Black square represents the apical region. (D) Representative sections and, number of positive cells per slide for PCNA marker. Black arrow heads indicating positive cells. (E) Representative sections and number of positive cells per field for CD163 marker. Black arrow heads indicating positive cells. n = 10 mice/group. Scale bar: 50 μm. Sections: 4 μm. *p < 0.05, **p < 0.01, ***p< 0.001, ****p < 0.0001 vs DSS. ^&p < 0.05, ^&&&&p < 0.0001 vs DSS + Eudragit-SBA-15.