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. 2024 Apr 17;14:8833. doi: 10.1038/s41598-024-58318-x

Table 2.

Changes in psychological flexibility, mindfulness, and values-congruent living.

Variable Overall time effect Mean (SE) change 2 weeks after placebo Mean (SE) change 2 weeks after psilocybin Difference (SE)
Acceptance and action questionnaire-II (AAQ-II) F(3,35) = 8.74, p < .001 1.94 (2.44), p = 0.433 10.64 (2.50), p = 0.0002 8.70 (2.46), p = 0.001
Valued living questionnaire (VLQ) F(3,36) = 2.99, p = 0.04 4.60 (3.32), p = 0.155 7.70 (3.32), p = 0.026 3.10 (3.27), p = 0.35
Observe (KIMS) F(3,36) = 0.72, p = 0.548 0.44 (1.41), p = 0.757 1.97 (1.49), p = 0.194 1.53 (1.41), p = 0.287
Awareness (KIMS) F(3,36) = 2.02, p = 0.129 1.18 (1.35), p = 0.39 3.37 (1.41), p = 0.023 2.20 (1.38), p = 0.121
Describe (KIMS) F(3,36) = 2.87, p = 0.05 1.41 (1.02), p = 0.176 2.63 (1.08), p = 0.02 1.22 (1.02), p = 0.237
Accept without judgment (KIMS) F(3,36) = 3.38, p = 0.029 3.38 (1.79), p = 0.068 5.81 (1.89), p = 0.004 2.43 (1.81), p = 0.188