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. 2024 Apr 17;14:8902. doi: 10.1038/s41598-024-58536-3

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Characteristics of serum-derived exosomes from CRC patients. (A) TEM presented exosome morphology with scale bars are 200 nm (left row) and 100 nm (right row). (B) Physical properties of exosomes show size distribution of serum-derived EVs including exosomes, as assessed by Zetasizer Nano. The curve depicts means, and standard deviations (SD) from three experiment replicates that yielded similar results.